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Correlation between clinical findings, mast cell count and interleukin 31 immunostaining in the skin of dogs with atopic dermatitis Ciência Rural
Gonçalves,Bárbara Hess Rodrigues; Matos,Bruna Dantas; Faleiro,Mariana Batista Rodrigues; Arnhold,Emmanuel; Matos,Moema Pacheco Chediak; Santin,Ana Paula Iglesias; Moura,Veridiana Maria Brianezi Dignani de.
ABSTRACT: In this study the correlation between the clinical score, mast cell count and interleukin 31 (IL-31) immunostaining in the skin of dogs with atopic dermatitis was determined. A total of 31 dogs of different breeds, from one to eight years of age, were chosen for the study. The 20 females and 11 males were categorized based on the CADESI-4 system, as having discrete, moderate or marked atopic dermatitis. Skin samples were collected from the axillary and interdigital regions and stained with hematoxylin and eosin for cytohistomorphological analyses and toluidine blue to evaluate the mast cell counts, and immunohistochemistry for the IL-31 immunostaining. Animals revealing higher atopic dermatitis scores had greater numbers of mast cells and IL-31...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Canine allergy; Pro-inflammatory cytokine; Toluidine blue.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000900600
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